North Staffordshire Joint Formulary
North Staffordshire Clinical Commissioning Group
Stoke-on-Trent Clinical Commissioning Group

 
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8 Malignant disease and immunosuppression

For the most up to date list of agents funded by the Cancer Drugs Fund, please see Cancer Drug Fund List

The list should be read in conjunction with Appraisal and Funding of Cancer Drugs from July 2016 (including the new Cancer Drugs Fund).

08-02-02 Corticosteroids and other immunosuppressants

Ciclosporin Cyclosporin
Formulary

All post-transplant immunosuppressants are RED for patients newly prescribed these medicines from April 2013

Brand must be stated

MHRA/CHM advice: ciclosporin must be prescribed and dispensed by brand name (December 2009)


Red View adult BNF  View SPC online  View childrens BNF
Tacrolimus
Formulary

All post-transplant immunosuppressants are RED for patients newly prescribed these medicines from April 2013

  • Prograf ®: immediate release capsule, twice daily dosage
  • Modigraf ®: immediate release formulation, twice daily dosage
  • Advagraf ®: prolonged release capsule, once daily dosage

Brands of other immediate release capsules taken twice daily include Adoport®, Capexion®, Tacni® and Vivadex®.

Switching between tacrolimus brands requires careful supervision and therapeutic monitoring by an appropriate specialist. Envarsus® is not interchangable with other oral Tacrolimus containing products.

 

MHRA/CHM advice: Oral tacrolimus products: prescribe and dispense by brand name only, to minimise the risk of inadvertent switching between products, which has been associated with reports of toxicity and graft rejection (June 2012)


Red View adult BNF  View SPC online  View childrens BNF
Ciclosporin
Formulary

Brand must be stated

MHRA/CHM advice: ciclosporin must be prescribed and dispensed by brand name (December 2009)

Link to ESCA


Amber E View adult BNF  View SPC online  View childrens BNF
Prednisolone
Formulary

All post-transplant immunosuppressants are RED for patients newly prescribed these medicines from April 2013

Prednisolone 1mg tablets
Prednisolone 5mg tablets


Red View adult BNF  View SPC online  View childrens BNF
Tacrolimus
Formulary
  • Prograf ®: immediate release capsule, twice daily dosage
  • Modigraf ®: immediate release formulation, twice daily dosage
  • Advagraf ®: prolonged release capsule, once daily dosage

Brands of other immediate release capsules taken twice daily include Adoport®, Capexion®, Tacni® and Vivadex®. 

Switching between tacrolimus brands requires careful supervision and therapeutic monitoring by an appropriate specialist. Envarsus® is not interchangable with other oral Tacrolimus containing products.

MHRA/CHM advice: Oral tacrolimus products: prescribe and dispense by brand name only, to minimise the risk of inadvertent switching between products, which has been associated with reports of toxicity and graft rejection (June 2012)

Link to ESCA


Amber E View adult BNF  View SPC online  View childrens BNF
Basiliximab Simulect®
Formulary

Restriction: In line with NICE Guidance only

Link  NICE TA481: Immunosuppressive therapy for kidney transplant in adults
Link  NICE TA482: Immunosuppressive therapy for kidney transplant in children and young people
 

Red View adult BNF  View SPC online  View childrens BNF  HCD